GACT15

with Arcadi Navarro, Juan A Rodriguez and David A. Hughes

Overview
Genome-Phenome analysis is both a challenging biological problem and a key component of precision medicine. This course aims to introduce current methods and concepts used to link genomes and phenomes. Emphasis will be placed on mapping disease susceptibility genes.
Course topics will be presented as lectures each followed by illustrative practical sessions. Topics will cover technological and design issues as well as current data analysis and interpretation strategies.
A variety of approaches to Genome-Phenome analysis will be covered ranging from array and targeted re-sequencing of (Epi-)Genome-Wide Association Studies to full genome re-sequencing. The main focus of this course will be on complex traits, however, the genetic architectures of cancer and rare diseases will also be considered.
Methods:
The course is comprised of practical exercises preceded by short lectures. There will be opportunities to hold group discussions on specific case studies.
Target Audiences:
(1) Individuals with knowledge about bioinformatics and/or genomics, that aim at using modern methods to address population variation or genotype phenotype association studies.
(2) Individuals interested in some particular phenotype(s) (MDs, veterinarians, biologists) and wishing to commence investigation of the genetics of their trait(s) of interest.
(3) All individuals, graduate or professional, wishing to expand on their working knowledge of the genetics of complex traits.